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Blood and Marrow Transplant

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If your child requires a blood and marrow transplant (BMT) or cellular therapy, you want the best care possible from a team of experienced medical professionals who care about your child as much as you do.

At Children’s Mercy, we have the resources, knowledge and expertise to not only help your child survive a life-threatening illness, but to thrive after treatment and live a healthy life.

Since the program began, more than 400 children have received life-saving blood and marrow transplants. 

Accredited care

Children's Mercy is accredited by FACT

 

Recognized by the Foundation for the Accreditation of Cellular Therapy

Our program is accredited by the Foundation for the Accreditation of Cellular Therapy (FACT) and the National Marrow Donor Program (NMDP). We are also a member of several organizations that help ensure your child receives the best care possible, including:

 
  • Center for International Blood and Marrow Transplant Research (CIBMTR)

  • Pediatric Blood and Marrow Transplant Consortium (PBMTC)

  • American Society for Blood and Marrow Transplantation

  • Children’s Oncology Group (COG)

Your blood and marrow transplant care team


The process of caring for a child who needs a transplant is complex and requires the skills and expertise of a team of specialists. All team members specialize in blood and marrow treatment.

Children’s Mercy is the pediatric consortium partner for the National Cancer Institute-designated The University of Kansas Cancer Center and the Stowers Institute for Medical Research. This partnership offers progress in cutting-edge cancer research to help the plight of children with cancer.

National Cancer Institute Logos

 

One of the first questions families ask us is will my child have a donor? When we meet a child in need of a transplant, we search all available donor options. Doing so means we can quickly find the best solution each child. As a transplant center for the National Marrow Donor Program, Children’s Mercy has access to donor registries throughout the world.

Advanced treatment for diverse disorders


Each year, the BMT Program performs approximately 40 transplants for children up to age 21. Transplants are done to treat varying forms and stages of cancers. We also use transplantation to treat immune system (immunologic) disorders, blood (hematologic) disorders, and metabolic disorders. We treat a wide range of diagnoses with transplant and have cared for many children with rare diseases through transplant.

 

Conditions

The wide range of diagnoses we treat with transplant include:

  • Acute Lymphoblastic Leukemia (ALL)

  • Acute Myelogenous Leukemia (AML)

  • Chronic Myelocytic Leukemia (CML)

  • Fanconi Anemia

  • Hodgkin’s Lymphoma

  • Hurler Syndrome

  • Juvenile Myelomonocytic Leukemia (JMML)

  • Non-Hodgkin’s Lymphoma

  • Severe Aplastic Anemia

  • Solid Childhood Tumors

  • Wilms tumor

  • Neuroblastoma

  • Sickle Cell Disease 

  • Thalassemia

Children’s Mercy also has experience with rare disorders, successfully treating:

  • Adrenoleukodystrophy (ALD)

  • Beta Thalassemia

  • Blackfan Diamond Syndrome

  • CD3 Delta Def

  • CD40 Ligand

  • Chediak-Higashi Syndrome

  • Congenital Dyserythropoietic Anemia

  • Crohn’s- IL-10 Receptor Mutation

  • Dyskeratosis Congenita

  • Glanzmann Thrombasthenia

  • Hemophagocytic lymphohistiocytosis (HLH)

  • Hurler Syndrome

  • I-Cell Disease

  • Omenn Syndrome

  • Osteopetrosis

  • Pansclerotic Morphea

  • Porphyria

  • Wiskott-Aldrich Syndrome

Research for advanced options

Research today leads to advanced treatment options for children who need transplant in the future. 

Learn more about the latest treatment options and research frontiers at Children's Mercy, like CAR T-cell immunotherapy and mini-transplants for children with SCID (severe immune system defect).

Stories

Aplastic anemia: Nick's story

One day Little League pitcher, Nick, just wasn't himself on the field. After a visit with his pediatrician, Nick was referred to Children's Mercy where the cause was diagnosed — a condition that hinders the bone marrow from making enough blood cells. See how Nick found the right treatment and even threw out the first pitch at a New York Yankees game.

Meet Nick
Nick's Story: an aplastic anemia patient at Children's Mercy

Beta thalassemia major: Hadil's story

Hadil, a Syrian refugee, had battled a rare inherited blood disorder since birth called beta thalassemia major. Now thanks to a successful bone marrow transplant at Children’s Mercy, where survival rates are at or above national averages, she is meeting the challenges of life in her new home.

Meet Hadil
Hadil's Story: beta thalassemia major

Refractory anemia with excess blasts: McKenzie's story

A winning athlete on the tennis court, McKenzie Haynes used that same spirit to meet the challenge of her young life—refractory anemia with excess blasts Type 1. Treatment at Children’s Mercy included blood transfusions, chemotherapy and a bone marrow transplant. Several months later, she was back on the court in top form.

Meet McKenzie
Refractory Anemia with Excess Blasts: McKenzie's Story

Triosephosphate isomerase deficiency: Wyatt's story

Four-year-old Wyatt was diagnosed with a rare genetic multisystem disorder called TPI shortly after he was born. A bone marrow transplant at Children’s Mercy, was his best chance for survival.

Meet Wyatt
Triosephosphate Isomerase Deficiency: Wyatt's Story

SCID: Connor's story

Connor's family chose Children's Mercy over many other options to care for Connor when he was born with X-linked severe combined immunodeficiency (SCID). Learn about his experience.

Contact the Blood and Marrow Transplant Team


Interested in learning more about the BMT program? Please contact the care team. 

Patients and families:
(816) 302-6808 

Referring health care providers:
(816) 302-6808
HOBMTNewPatientReferral@cmh.edu