Anaphylaxis
Clinical Pathways promote evidence based, safe, and high-value care for patients by providing clinical recommendations and standard processes. They are developed by multidisciplinary committees of subject matter experts, informed by methodical review of available evidence and consensus among committee members.
Clinical Pathway:
- Anaphylaxis Algorithm
- Anaphylaxis Synopsis (provides care standards employed for this clinical pathway)
Additional tools associated with this Clinical Pathway:
Inclusion and exclusion criteria:
Inclusion:
- Diagnosed and/or suspected anaphylaxis
Exclusion:
- Local allergic reaction
- Mild allergic reaction
- For patients with oncologic conditions managed oncology, please refer to the Infusion Reaction in Hem/Onc Patient CPM
Committee members involved in the development:
- Amanda Nedved, MD | Urgent Care | Committee Chair
- Nicholas Clark, MD, FAAP, CPHQ | Hospital Medicine | Committee Member
- Katelyn Shaw, PharmD | Pharmacy | Committee Member
- Jennifer McKinsey, MD | Urgent Care | Committee Member
- Emily Bonanni, MD | Hospital Medicine | Committee Member
- Cara Holton, MD | Critical Care Medicine | Committee Member
- Ashly Daniel, MD | Critical Care Medicine | Committee Member
- Jay Portnoy, MD | Allergy, Asthma, and Immunology | Committee Member
- Allison Hadley, MD, FAAP | Emergency Department | Committee Member
Patient/Family Committee Member:
- Mandi Kearns | Committee Member
EBP Committee Members:
- Kathleen Berg, MD, FAAP | Hospital Medicine and Evidence Based Practice | Committee Member
- Jarrod Dusin, MS, RD, LD, CQHP | Evidence Based Practice | Committee Member
Publication dates:
- Finalized date: 02/23
- Next expected revision date: 2026
If you have any questions regarding this content or identify a broken link, please email evidencebasedpractice@cmh.edu.
These pathways do not establish a standard of care to be followed in every case. It is recognized that each case is different, and those individuals involved in providing health care are expected to use their judgment in determining what is in the best interests of the patient based on the circumstances existing at the time. It is impossible to anticipate all possible situations that may exist and to prepare a pathway for each. Accordingly, these pathways should guide care with the understanding that departures from them may be required at times.
These pathways do not establish a standard of care to be followed in every case. It is recognized that each case is different, and those individuals involved in providing health care are expected to use their judgment in determining what is in the best interests of the patient based on the circumstances existing at the time. It is impossible to anticipate all possible situations that may exist and to prepare a pathway for each. Accordingly, these pathways should guide care with the understanding that departures from them may be required at times.