Research Studies and Clinical Trials Search
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Remote CaRe: An in-home cardiac rehabilitation study for adolescents with congenital heart disease
This study is for: • Adolescents, aged 12-19 years old • Diagnosed with one of three congenital heart diseases: Fontan physiology, Tetralogy of Fallot, or D-Transposition of the great arteries"...
This study is for: • Adolescents, aged 12-19 years old • Diagnosed with one of three congenital heart diseases: Fontan physiology, Tetralogy of Fallot, or D-Transposition of the great arteries" This study aims to see if 12-weeks of in-home cardiac rehab (exercise training) using live video conferencing software can increase physical fitness in adolescents with congenital heart disease. To learn more about this study please watch this video: https://www.youtube.com/watch?v=2oOt5lTL1ow You can call or text us at 816-764-5605
Single Ventricle Condition: A Clinical Trial of a Medication to Increase Exercise Endurance for Adolescents who had a Fontan Procedure
This study is for children: • Age 12-18 years old • Born with a single ventricle and had a Fontan procedure • Currently on blood thinner (i.e. taking medications such as aspirin, heparin, coumadin/warfarin, etc.)...
This study is for children: • Age 12-18 years old • Born with a single ventricle and had a Fontan procedure • Currently on blood thinner (i.e. taking medications such as aspirin, heparin, coumadin/warfarin, etc.) The purpose of this study is to find out if the investigational study drug, udenafil, is effective and safe in adolescent participants who have single ventricle heart disease (SVHD) and have undergone a Fontan procedure. Udenafil works to help dilate (open) the blood vessels, which allows for better function of the heart and lungs. The study aims to (1) find out how well udenafil works to improve a patient's ability to exercise and perform everyday activities (2) potentially prevent liver fibrosis, a common complication of SVHD. Patients who participate in the study will be randomly assigned, like flipping of a coin, to receive either udenafil or placebo (does not contain active medication) and have an equal chance (50%) of receiving either udenafil or placebo. Participants will take one tablet by mouth, twice a day, for 26 weeks and be in the study for approximately 7 months.
Single Ventricle Heart Condition: How Skeletal Muscle Health Contributes Toward Overall Health
This study is for children: • 12-18 years old • Born with a single ventricle heart and had the Fontan Procedure • Be able to wear an accelerometer for a week. (Accelerometer is a small device worn on the hip to measure physical...
This study is for children: • 12-18 years old • Born with a single ventricle heart and had the Fontan Procedure • Be able to wear an accelerometer for a week. (Accelerometer is a small device worn on the hip to measure physical activity) OR • 12-18 years old • Born with a normal heart (comparison group) • Be able to wear an accelerometer for a week. (Accelerometer is a small device worn on the hip to measure physical activity) The goal of the research study is to better understand the importance of skeletal muscle health (especially leg muscles) and how it contributes to the overall health of an adolescent living with a single ventricle heart. Researchers know that healthy muscles play a larger role in helping blood return to the lungs in these adolescents, but they do not understand the details of this relationship. In addition, adolescents with normal hearts will be enrolled as a comparison group.