Research Studies and Clinical Trials Search
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Cystic Fibrosis-Related Diabetes: A Study Comparing the Safety of the Bionic Pancreas Device Relative to Usual Care.
This study is being done to learn how well the iLet Bionic Pancreas system works in patients with Cystic Fibrosis-Related Diabetes (CFRD). - 14 years old or older - Have Cystic Fibrosis Related Diabetes...
This study is being done to learn how well the iLet Bionic Pancreas system works in patients with Cystic Fibrosis-Related Diabetes (CFRD). - 14 years old or older - Have Cystic Fibrosis Related Diabetes - Be on treatment of insulin for at least 3 months
Prediabetes/Diabetes, Polycystic Ovary Syndrome (PCOS), Rapid Weight Gain, and/or Insulin Resistance: A study of metformin in youth ages 7 to 21 years old
Researchers at Children's Mercy want to learn more about Metformin. Metformin is a pill dosed every day to treat things like insulin resistance and diabetes. The purpose of this study is to learn how Metformin is processed in the body and to discover how to best dose Metformin in...
Researchers at Children's Mercy want to learn more about Metformin. Metformin is a pill dosed every day to treat things like insulin resistance and diabetes. The purpose of this study is to learn how Metformin is processed in the body and to discover how to best dose Metformin in children. This study is for children currently taking Metformin between the ages 7 to 21 years old.
Type 1 Diabetes Stage 2: A study to possibly prevent or delay progression to Stage 3 T1D
This study is for children: • Able to have low dose Antithymocyte Globulin (ATG) • Able to have infusion therapy...
This study is for children: • Able to have low dose Antithymocyte Globulin (ATG) • Able to have infusion therapy The goal of this study is to learn if ATG can help prevent or delay progression to clinical diagnosis of type 1 diabetes in people that is having multiple autoantibodies with abnormal glucose status (called stage 2 diabetes) and at least one of the high-risk marker(s) who are at greater risk of progression to clinical diabetes.
Type 1 Diabetes: A study of Garmin Vivosmart devices to measure change in physical activity
This study is for youths: -8-21 years old -With a diagnosis of Type 1 Diabetes -Who are patients in the Children's Mercy Kansas City...
This study is for youths: -8-21 years old -With a diagnosis of Type 1 Diabetes -Who are patients in the Children's Mercy Kansas City The goal of this study is to see if wearing the Garmin physical activity tracker increases activity and control over Type 1 diabetes (T1D). Another purpose is to see if wearing the Garmin tracker changes how people feel about managing their diabetes. The study will look at activity levels, blood sugar, hospital admissions, time in range, A1c, and reported activity levels. The study also will ask about feelings about T1D and managing T1D in surveys for both patients and parents of child patients.
Type 1 Diabetes: A study of the Happy Bob App
This study is being done for teens: • Ages 13-17 years old • Diagnosed with Type 1 Diabetes • Own/Use an iPhone to view Dexcom readings...
This study is being done for teens: • Ages 13-17 years old • Diagnosed with Type 1 Diabetes • Own/Use an iPhone to view Dexcom readings The goal of the study is to see what impact the Happy Bob app has on diabetes management, mood, feelings of peer support, and more. The app connects to Dexcom and sends users time in range notifications in the personality of their choosing - Happy Bob, Snarky Bob, Pumpkin Bob, Snowman Bob, and more. Users can also earn awards in the app and join the Children's Mercy Teens group page to encourage one another with posts and respond to fun icebreaker questions, among other features.
Type 1 Diabetes: A study of the oral medication DFMO in newly diagnosed type 1 diabetic children and adults for treatment.
This study is being done for children/adults: -Newly diagnosed (within past 100 days) type 1 diabetes -Ages 6-40 years...
This study is being done for children/adults: -Newly diagnosed (within past 100 days) type 1 diabetes -Ages 6-40 years DFMO is a medication taken by mouth which may reduce the stress of cells that make insulin and preserve body's own insulin production.
Type 1 Diabetes: A study to help preserve remaining insulin secretion
This study is being done for children/adults: • With type 1 Diabetes Diagnosis • Able to wear a Continuous Glucose Monitoring...
This study is being done for children/adults: • With type 1 Diabetes Diagnosis • Able to wear a Continuous Glucose Monitoring This study is to see if giving the medications rituximab-pvvr (Ruxience®) followed by abatacept can help preserve remaining insulin secretion if given within three months of being diagnosed with type 1 diabetes (T1D).This study will help researchers to learn more about how to help people with diabetes Type 1.
Type 1 Diabetes: Reduce feelings of diabetes distress
This study is for children: • Ages 8-12.99 • Who have Type 1 Diabetes • Are on intensive insulin treatment...
This study is for children: • Ages 8-12.99 • Who have Type 1 Diabetes • Are on intensive insulin treatment • English is their primary language The purpose of this research study is to test whether a treatment program works to help families of school-age children with T1D reduce any feelings of diabetes distress and improve glucose levels. Families participate via a computer, tablet, or smartphone. Families will also upload continuous glucose monitoring (CGM) data.
Type 1 or Type 2 Diabetes: A Study to Continuous Monitoring and Control of Hyploglycemia
This study is being done for young adults: • Be at least 18 years or older. • Have been diagnosed with Type 1 or Type 2 diabetes mellitus with at least one (1) week of being on insulin at time of study entry...
This study is being done for young adults: • Be at least 18 years or older. • Have been diagnosed with Type 1 or Type 2 diabetes mellitus with at least one (1) week of being on insulin at time of study entry. • Use a smartphone and/or have access to a computer The purpose of the study is to confirm the safety of using the Continuous Glucose Monitoring CGM System for making diabetes treatment decisions instead of fingerstick testing.
Type I Diabetes: A study on the effect of individualized eating plans for teens
This study is for teens: -12-17 years old -T1D Diagnosis for 1+ years...
This study is for teens: -12-17 years old -T1D Diagnosis for 1+ years -Last HbA1c test 7.2+ The purpose of this research study is to see if a personalized eating plan that spaces out carbohydrates evenly throughout the day is something teens can follow and is helpful for their glycemic management. The research will study how closely the eating plan is followed. Average blood glucose at the beginning of the study will also be compared with average blood glucose at the end of the study to see if blood glucose control is related to following an eating plan. The total duration of project participation is 6 months.
Type I Diabetes: A study on two interventions to improve blood sugar control
This study is for teenagers: • Diagnosed with type 1 diabetes • Between 12-17 years old • Currently using an insulin pump for insulin delivery...
This study is for teenagers: • Diagnosed with type 1 diabetes • Between 12-17 years old • Currently using an insulin pump for insulin delivery The overall purpose of this study is to help adolescents with Type 1 Diabetes (T1D) follow their treatment plans. T1D is a serious disease that happens because the body cannot control blood glucose (sugar) levels. It is very common for adolescents to forget to give an insulin bolus for meals. When insulin doses are missed, there is a greater chance for poor blood sugar control. It is very common for adolescents to forget to give an insulin bolus for meals. When insulin doses are missed, there is a greater chance for poor blood sugar control. When adolescents follow their diabetes plan closely, they have better blood sugar control and overall health.
Type I Diabetes: A study to better understand those at risk for developing Type I Diabetes
The overall objective of this study is to perform baseline and repeat assessments over time of the metabolic and immunologic status of individuals at risk for type 1 diabetes (T1D) to: (a) characterize their risk for developing T1D and identify subjects eligible for prevention...
The overall objective of this study is to perform baseline and repeat assessments over time of the metabolic and immunologic status of individuals at risk for type 1 diabetes (T1D) to: (a) characterize their risk for developing T1D and identify subjects eligible for prevention trials, (b) describe the pathogenic evolution of T1D, and (c) increase the understanding of the pathogenic factors involved in the development of T1D.
Type I Diabetes: A study to observe the preservation of C-peptides in the pancreas of children newly diagnosed with Type I Diabetes
This study is being done for children and adults: • Age 12-35 • Within 100 days of being newly diagnosed with Type I Diabetes (T1D) • At least 1 autoantibody positive...
This study is being done for children and adults: • Age 12-35 • Within 100 days of being newly diagnosed with Type I Diabetes (T1D) • At least 1 autoantibody positive • Mixed Meal Tolerance Tests with most visits Researchers are performing this study to observe the preservation of C-peptides in the pancreas of children newly diagnosed with T1D. The goal of this study is to learn if either abrocitinib or ritlecitinib could help delay or stop further destruction of remaining beta cells in people recently diagnosed with Type I Diabetes (T1D). Researchers will follow people in the study by performing blood tests and will collect information about their diabetes to learn more about how these drugs work.
Youth with Insulin Treated Diabetes: A study to collect feedback on a diabetes phone app
This study is for: - Participants include Parent(s)/Guardians of children age 1-18 who have insulin treated diabetes or youth age 13-22 who have insulin treated diabetes The goal of this study is to test if a diabetes phone app has an impact on engagement and understanding of...
This study is for: - Participants include Parent(s)/Guardians of children age 1-18 who have insulin treated diabetes or youth age 13-22 who have insulin treated diabetes The goal of this study is to test if a diabetes phone app has an impact on engagement and understanding of diabetes care.