Research Studies and Clinical Trials Search
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Brain Response to Medicines: A study to learn how the brain of a person with ADHD or depression responds to medicine
This study is being done for: -Children and adults ages 7 to 25 years old -Children and adults with ADHD previously enrolled in the ATX PBPK-PD-Clinical Outcomes Study at Children's Mercy -Children and adults with depression who previously participated in the GOLDILOKs PRISM...
This study is being done for: -Children and adults ages 7 to 25 years old -Children and adults with ADHD previously enrolled in the ATX PBPK-PD-Clinical Outcomes Study at Children's Mercy -Children and adults with depression who previously participated in the GOLDILOKs PRISM Study at Children's Mercy The goal of the study is to learn more about how exactly brain cells respond to ADHD and/or depression medicines and learn if researchers can predict whether a child or adult's ADHD or depression symptoms will improve with these certain medicines.
Depression: A study of fluoxetine (Prozac®) and escitalopram (Lexapro®) in teens and adolescents
This study is for teens: • Ages (12-18) • With depression diagnosis The goal of this study is to understand why the antidepressant medicines fluoxetine (Prozac®) and escitalopram...
This study is for teens: • Ages (12-18) • With depression diagnosis The goal of this study is to understand why the antidepressant medicines fluoxetine (Prozac®) and escitalopram (Lexapro®) work for some teens with depression and not for others. Every teen and their depression are unique, and there is no one-size fits all treatment. What researchers learn from this study could help the care team find the right treatment sooner, which could lead teens on a quicker path to recovery.
Improve treatment: Understanding the amount of fluoxetine, escitalopram, pimozide, pantoprazole, and lansoprazole that reaches the brain in teens and young adults
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires...
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires The goal of this study is to measure the amount of certain medications in the brain.
Parenting Teens Videos & Toolkit: Caregiver Survey
This study aims to get feedback from parents and caregivers about a series of videos they watch about parenting teenagers. Those who can participate are: • A parent or caregiver who is willing to: 1. Watch a series of 3-5 minute videos (in total lasting ~40 minutes) and...
This study aims to get feedback from parents and caregivers about a series of videos they watch about parenting teenagers. Those who can participate are: • A parent or caregiver who is willing to: 1. Watch a series of 3-5 minute videos (in total lasting ~40 minutes) and 2. Complete online surveys. Researchers are providing education about steps parents can take to improve the health and safety of their children as they become teens. The aim is to help parents learn what steps can be taken before a crisis develops with their teenager. The "Prepped and Ready" video presentations provides a brief overview on the following topics, with an emphasis on suicide prevention: -Eating disorder prevention -Home safety (including storage of firearms, medications, etc.) -Self-care -Substance use (including vaping) -Suicide prevention To learn if this education is helpful, researchers hope to learn about parents experience of attending the talk, and what parents learn. Researchers also want to understand what steps parents may take after the talk and what barriers they encounter.
Tourette's Disorder: A study on Ecopipam tablets in patients with Tourette's Disorder
This study uses the medication Ecopipam to treat Tourette's Disorder. The main purpose is to learn how well Ecopipam (the study drug) works when taken continuously, and how safe Ecopipam is compared to a placebo (an inactive material that looks like the study drug, but doesn't...
This study uses the medication Ecopipam to treat Tourette's Disorder. The main purpose is to learn how well Ecopipam (the study drug) works when taken continuously, and how safe Ecopipam is compared to a placebo (an inactive material that looks like the study drug, but doesn't have any active study drug). - Age range: Children (6 and older), adolescents and adults (>18 years old). - Must have a diagnosis of Tourette's Disorder. - Participation in the study lasts approximately 30 weeks (7 months).
Turner Syndrome (TS), The Brain, and Hormone Replacement Therapy (HRT): A study evaluating brain structure and function in adolescents and young adults with Turner syndrome who use hormone replacement therapy as compared to those without Turner syndrome
This study is for teen girls and young adult women: • Ages 14-21 years • With and without Turner syndrome...
This study is for teen girls and young adult women: • Ages 14-21 years • With and without Turner syndrome The goal of this study is to understand how hormones from the ovaries affect brain development. Every person is unique and the ovaries of some teens and young adults do not produce enough hormones. What researchers learn from this study could help the care team find better treatments for teens and young adults whose ovaries do not make enough hormones.
Type I Diabetes: A study on the effect of individualized eating plans for teens
This study is for teens: -12-17 years old -T1D Diagnosis for 1+ years...
This study is for teens: -12-17 years old -T1D Diagnosis for 1+ years -Last HbA1c test 7.2+ The purpose of this research study is to see if a personalized eating plan that spaces out carbohydrates evenly throughout the day is something teens can follow and is helpful for their glycemic management. The research will study how closely the eating plan is followed. Average blood glucose at the beginning of the study will also be compared with average blood glucose at the end of the study to see if blood glucose control is related to following an eating plan. The total duration of project participation is 6 months.