Research Studies and Clinical Trials Search
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Anxiety and Depression: A study of how the body breaks down medicine
This study involves: - Children and teens age 6-18 - Taking the prescribed medicine every day for 2 weeks without missing any doses - A one-time 24- or 12-hour visit in the Pediatric Clinical Research Unit...
This study involves: - Children and teens age 6-18 - Taking the prescribed medicine every day for 2 weeks without missing any doses - A one-time 24- or 12-hour visit in the Pediatric Clinical Research Unit Researchers at Children's Mercy are doing this study to learn more about how the body breaks down medicine for depression, anxiety, or ADHD. Children and teens who are prescribed fluoxetine (Prozac®), sertraline (Zoloft®), escitalopram (Lexapro®), and/or atomoxetine (Strattera®) are eligible to participate.
Brain Response to Medicines: A study to learn how the brain of a person with ADHD or depression responds to medicine
This study is being done for: -Children and adults ages 7 to 25 years old -Children and adults with ADHD previously enrolled in the ATX PBPK-PD-Clinical Outcomes Study at Children's Mercy -Children and adults with depression who previously participated in the GOLDILOKs PRISM...
This study is being done for: -Children and adults ages 7 to 25 years old -Children and adults with ADHD previously enrolled in the ATX PBPK-PD-Clinical Outcomes Study at Children's Mercy -Children and adults with depression who previously participated in the GOLDILOKs PRISM Study at Children's Mercy The goal of the study is to learn more about how exactly brain cells respond to ADHD and/or depression medicines and learn if researchers can predict whether a child or adult's ADHD or depression symptoms will improve with these certain medicines.
Improve treatment: Understanding the amount of fluoxetine, escitalopram, pimozide, pantoprazole, and lansoprazole that reaches the brain in teens and young adults
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires...
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires The goal of this study is to measure the amount of certain medications in the brain.
Parenting Teens Videos & Toolkit: Caregiver Survey
This study aims to get feedback from parents and caregivers about a series of videos they watch about parenting teenagers. Those who can participate are: • A parent or caregiver who is willing to: 1. Watch a series of 3-5 minute videos (in total lasting ~40 minutes) and...
This study aims to get feedback from parents and caregivers about a series of videos they watch about parenting teenagers. Those who can participate are: • A parent or caregiver who is willing to: 1. Watch a series of 3-5 minute videos (in total lasting ~40 minutes) and 2. Complete online surveys. Researchers are providing education about steps parents can take to improve the health and safety of their children as they become teens. The aim is to help parents learn what steps can be taken before a crisis develops with their teenager. The "Prepped and Ready" video presentations provides a brief overview on the following topics, with an emphasis on suicide prevention: -Eating disorder prevention -Home safety (including storage of firearms, medications, etc.) -Self-care -Substance use (including vaping) -Suicide prevention To learn if this education is helpful, researchers hope to learn about parents experience of attending the talk, and what parents learn. Researchers also want to understand what steps parents may take after the talk and what barriers they encounter.
Turner Syndrome (TS), The Brain, and Hormone Replacement Therapy (HRT): A study evaluating brain structure and function in adolescents and young adults with Turner syndrome who use hormone replacement therapy as compared to those without Turner syndrome
This study is for teen girls and young adult women: • Ages 14-21 years • With and without Turner syndrome...
This study is for teen girls and young adult women: • Ages 14-21 years • With and without Turner syndrome The goal of this study is to understand how hormones from the ovaries affect brain development. Every person is unique and the ovaries of some teens and young adults do not produce enough hormones. What researchers learn from this study could help the care team find better treatments for teens and young adults whose ovaries do not make enough hormones.