Research Studies and Clinical Trials Search
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Capture IBD: A tool used to collect information about Irritable Bowel Disease
This study is for children and young adults: • 4-21 years old • Who have or may have Irritable Bowel Disease (e.g., Ulcerative Colitis, Crohn's)...
This study is for children and young adults: • 4-21 years old • Who have or may have Irritable Bowel Disease (e.g., Ulcerative Colitis, Crohn's) This study will develop a research resource for future studies of IBD, including Crohn's disease and ulcerative colitis, and other inflammatory diseases and diseases of the intestines. This resource will be available to scientists to answer many questions about treatments, therapies, and surgeries for patients with IBD.
CHAMP GI: A remote tube weaning study using CHAMP® App
This study is for children who are: • Ages 1 month to 5 years 11 months • Approved for tube weaning by Children's Mercy Interdisciplinary Feeding Clinic providers The goal of this study is to evaluate the use of data collection while at home and using the CHAMP® App during a...
This study is for children who are: • Ages 1 month to 5 years 11 months • Approved for tube weaning by Children's Mercy Interdisciplinary Feeding Clinic providers The goal of this study is to evaluate the use of data collection while at home and using the CHAMP® App during a feeding tube weaning period. Tube weaning can be a stressful time, and researchers are interested in finding ways to make the experience better. Researchers are trying to learn if the CHAMP App would be a helpful tool for parents and providers to support monitoring children that are tube feeding because of feeding difficulties.
Colectomy for Familial Adenomatous Polyposis (FAP): A study of tissue samples to understand bacteria in the gut
This study is currently enrolling patients who: • Are ages 7 to 20 years • Have been diagnosed with Familial Adenomatous Polyposis • Have been referred to colectomy within 12 months of surveillance colonoscopy...
This study is currently enrolling patients who: • Are ages 7 to 20 years • Have been diagnosed with Familial Adenomatous Polyposis • Have been referred to colectomy within 12 months of surveillance colonoscopy Familial Adenomatous Polyposis (FAP) is an inherited syndrome where polyps develop in the gut and will become cancerous. The purpose of this research study is to learn more about the relationship between bacteria in the gut and polyps. Being in this study involves the participant providing a stool sample and a blood sample. The parent/guardian will also give the study team permission to take tissue samples from their child's colon once it has been removed.
Colonoscopy with or without Polyposis: Tissue samples collected for research on cancer prevention and treatment
This study is currently enrolling patients who: • Are ages 1 month to 21 years • Have been diagnosed with polyposis, either clinically or through genetic testing with adenomas found on colonoscopy...
This study is currently enrolling patients who: • Are ages 1 month to 21 years • Have been diagnosed with polyposis, either clinically or through genetic testing with adenomas found on colonoscopy The main purpose of this study is to use normal tissues (not polyps) and non-normal tissues (polyps) to test candidate drugs or compounds against and ensure there is not significant toxicity to these normal cells. A study participant will have biopsies of tissue collected from different locations in their intestinal tract. The tissues will be stored in a way that allows cell to grow and multiply. The cell lines that potentially grow will be used to test the toxicity of the drugs or compounds that are being tested to see if they possibly help tissue affected by polyposis.
Gastroenterology Repository: A tool used to collect information for future and current research
This study is enrolling patients age 6 months to 23 years of age who have been seen by a Children's Mercy gastroenterologist or other providers and are undergoing any standard of care procedure or visit at which time samples could be collected for the repository.
This study is enrolling patients age 6 months to 23 years of age who have been seen by a Children's Mercy gastroenterologist or other providers and are undergoing any standard of care procedure or visit at which time samples could be collected for the repository.
Gastrojejunal (G-J Tube): A study on megestrol to transition children to oral feeding
This study is being done for children: • 9 months to 9 years old • Who are dependent on g-tube for at least 80% of daily caloric intake • Have the motor and emotional skills necessary to eat by mouth...
This study is being done for children: • 9 months to 9 years old • Who are dependent on g-tube for at least 80% of daily caloric intake • Have the motor and emotional skills necessary to eat by mouth The goal of this study is to transition children from g-tube to all oral feeding. Study lasts 6 months and includes bi-weekly, remote coaching sessions, 4 in-person visits and a 50% chance of receiving megestrol, a medication used to stimulate appetite.
GI pathologies detection: A tool used to collect information for future developments.
This study is for patients: • Having a capsule endoscopy The study purpose is to collect PillCamTM SB3 videos/cases to support future development and validation of improved algorithms and technics for pathologies detection in the GI.
This study is for patients: • Having a capsule endoscopy The study purpose is to collect PillCamTM SB3 videos/cases to support future development and validation of improved algorithms and technics for pathologies detection in the GI.
Improve treatment: Understanding the amount of fluoxetine, escitalopram, pimozide, pantoprazole, and lansoprazole that reaches the brain in teens and young adults
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires...
This study is being done for teens and young adults: • Ages 12 to 21 • Currently taking or recently stopped taking fluoxetine, escitalopram, pimozide, pantoprazole, or lansoprazole • Able to have a special brain scan (MRI), a blood draw, and answer brief questionnaires The goal of this study is to measure the amount of certain medications in the brain.
Inflammatory Bowel Disease: Transitioning to Adult Care Survey
This study is for: • Those who are diagnosed with Inflammatory Bowel Disease (IBD) • Are between ages 15-22 • Both patients with IBD and their caregivers...
This study is for: • Those who are diagnosed with Inflammatory Bowel Disease (IBD) • Are between ages 15-22 • Both patients with IBD and their caregivers The purpose of this research study is to understand the things that make it difficult for a young person living with IBD to transition from a pediatric GI doctor to an adult GI doctor. By being in this study, it may help researchers learn how to better work with patients moving to adult health care.
MUAC Z-score tape: Monitoring malnutrition for pediatric patients.
This study is being done for children and parents: • Children who are being seen in the GI Interdisciplinary Feeding and Swallowing Program. • Parents will complete a one-time survey to determine if they can accurately obtain infant/child MUAC Z-score measurements using CMH...
This study is being done for children and parents: • Children who are being seen in the GI Interdisciplinary Feeding and Swallowing Program. • Parents will complete a one-time survey to determine if they can accurately obtain infant/child MUAC Z-score measurements using CMH MUAC Z-score tapes provided to them. This study begins with teaching parents how to measure at visit one, then they demonstrate a measurement at visit two on their own and get reteaching if needed. Once that is completed, the survey is sent to the parent to see how they felt about the education and feasibility of actually measuring on their child.